Targeted cancer therapies are drugs or other substances that block the growth and spread of cancer by interfering with specific molecules involved in tumor growth and progression.
Because scientists call these specific molecules “molecular targets,” therapies that interfere with them are sometimes called “molecularly targeted drugs,” “molecularly targeted therapies,” or other similar names.
Targeted cancer therapies that have been approved for use in specific cancers include drugs that interfere with cell growth signaling or tumor blood vessel development, promote the specific death of cancer cells, stimulate the immune system to destroy specific cancer cells, and deliver toxic drugs to cancer cells.
These agents work via blockage of specific receptors involved in cell growth. They are often used in combination with standard chemotherapy agents to enhance their effectiveness, or as part of an ongoing clinical trial.
Click here to read the article: “Advanced ovarian cancer: What should be the standard of care?” by Barbara A. Goff in the Journal of Gynecological Oncology, January 8, 2013.